Dear HD Friends and Families,
March 27, 2018
March 26, 2018 marked 25 years since the identification of the gene that causes Huntington’s disease. The discovery of the repeating CAG sequence in the DNA was made in 1993 by the Huntington’s Disease Collaborative Research Group, an assembly of scientists across six institutions. They had united nearly a decade earlier, in 1984, after Jim Gusella’s work had narrowed the search down to chromosome 4. Integral to this discovery was a huge community of families affected by HD in the Lake Maracaibo region of Venezuela, as well as families in the USA, who donated their blood and their time so that the researchers could study their genes and connect the dots. The 20-year Venezuela study was championed by Nancy Wexler, and when the gene was finally identified, the published paper had nearly sixty individual authors.
Twenty-five years later the HD community is on the brink of an unprecedented clinical trial that focuses on the HD gene itself and aims to reduce levels of the harmful huntingtin protein. This progress was made through extraordinary collaborative effort among researchers and families.
We are appealing to you to support the search for a cure.
Your gift will help the scientists stop this devastating disease. Please join me and other HDSA Northern California Board Members by making a donation today.
You can make your tax-deductible contribution in one of two ways.
1. By Mail
Click the link below to make your donation. (Steps for both options are listed.)
Make a donation to help find a cure
We thank you for your continued support.